Causes of Bone Cancer (Osteosarcoma)
Children's who have inherited some rare cancer disorders are more prone to osteosarcoma. These disorders include erasure of 13q14 chromosome which automatically deactivates retinoblastoma gene (a cancerous tumor that develops in the Retina) and Li- Fraumeni syndrome- a kind of genetic mutation. If some cases, children's who have previously undergone through radiotherapy for some other cancer treatment are at increased risk for Osteosarcoma because exposure to radiations can cause DNA mutation.
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